Polyethylene Oxide (PEO) Dị Elu nke Polyethylene Oxide | Matrix Mwepụta Kwadoro maka Mbadamba Hydrophilic | Dabara na USP/EP/ChP

Polyethylene Oxide nke Ọgwụ anyị (PEO) bụ homopolymer dị arọ molekul dị elu, nke mmiri na-agbaze nke na-adịghị agbaze, nke dị na ọkwa viscosity dị iche iche (ibu molekul site na 100,000 ruo 7,000,000)Ọ na-arụ ọrụ dị ka ihe na-enye aka dị iche iche maka ụdị ọgwụ siri ike a na-aṅụ. Ojiji ndị dị mkpa gụnyere: matrix na-adịgide adịgide (mmiri ngwa ngwa na nhazi gel maka awa iri ma ọ bụ karịa nke mwepụta ọgwụ)ihe na-ejikọ ọnụ nke mucous maka sistemu afọ na eriri afọ, ihe njide maka granulation na mkpakọ kpọmkwem, na ihe na-emepụta ihe nkiri maka ihe nkiri dị gịrịgịrị na mkpuchi ngwaọrụ ahụikeDabara na ọgwụ USP-NF, EP, na ChP site na ndebanye aha CDE F20220000511Nwere mmiri mmiri ngwa ngwa, ikike ịba ụba dị elu, njirimara thermoplastic, na ọdịdị na-adịghị mma (enweghị ụtọ, enweghị agba)

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Nkọwa Ngwaahịa

Ọgwụ Polyethylene Oxide (PEO)

Nchịkọta Ngwaahịa

Polyethylene Oxide (PEO) bụ homopolymer nke ethylene oxide na-abụghị ionic, nke usoro H(OCH2CH2)nOH nọchitere anya ya, ebe n na-anọchite anya ọnụọgụgụ nke otu oxyethylene dị site na ihe dị ka 2,000 ruo 200,000.Ọ bụ polima dị arọ nke nwere oke molekul, nke a na-agbaze mmiri nke ukwuu, a na-ejikarị ya eme ihe dị ka ihe na-enye ọgwụ n'ụdị mwepụta a na-achịkwa, ihe ndị na-ejikọ granulation, ihe mkpuchi ihe nkiri, na sistemụ nnyefe ọgwụ mucoadesive..

Njirimara Ngwaahịa:

Aha Kemịkalụ:Polyethylene oxide
Nọmba CAS:68441-17-8 / 25322-68-3
Nọmba Ndebanye Aha CDE:F20220000511
Nrubeisi nke Pharmacopoeia:ChP (CP2020), USP-NF, EP
Ọdịdị:Ntụ ntụ ọcha ruo ọcha, nke na-agbapụta n'enweghị ntụpọ, nwere obere isi ammonia
Mgbaze:A na-agbaze n'ime mmiri na ọtụtụ ihe mgbaze organic a na-ahụkarị (acetonitrile, chloroform, dichloromethane); anaghị agbaze na aliphatic hydrocarbons, ethylene glycol, na ethanol